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品种反应性 主要应用 宿主 格式 抗体类型 Sh, B, Ca, Gp, H, R WB, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB1569 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Dopa Decarboxylase Antibody 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. 应用 应用 Detect Dopa Decarboxylase using this Anti-Dopa Decarboxylase Antibody validated for use in IH & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunoblotting: 1:500-1:1,000
Immunohistochemistry using formaldehyde-fixed brain sections.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant bovine DDC expressed in E. coli and purified from inclusion bodies. 宿主 Rabbit 特异性 DOPA Decarboxylase (DDC). Reacts with a single band of ~55 kDa by Western blot. 品种反应性 SheepBovineCanineGuinea PigHumanRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001082971.1
- NM_000790.3
基因符号 - EC 4.1.1.28
- DDC
- AADC
UniProt编号 - P20711
UniProt汇总 FUNCTION: SwissProt: P20711 # Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
COFACTOR: Pyridoxal phosphate.
SIZE: 480 amino acids; 53894 Da
SUBUNIT: Homodimer.
DISEASE: SwissProt: P20711 # Defects in DDC are the cause of aromatic-L-amino-acid decarboxylase deficiency (AADC deficiency) [MIM:608643]. AADC deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive.
SIMILARITY: SwissProt: P20711 ## Belongs to the group II decarboxylase family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20 to -80°C in undiluted aliquots for up to six months after date of receipt. Store in a NON-self-defrosting freezer. Avoid repeated freeze-thaw cycles. 包装信息 数量 100 µL
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