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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Sh, H, M, R, Rb WB, ICC Rb Serum Polyclonal Antibody 描述 产品目录编号 AB1565 Replaces AB937 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Vasopressin Antibody 产品信息 格式 Serum 控制 - Hypothalamus
演示 Neat rabbit antisera. Liquid, with 0.1% sodium azide. 应用 应用 Anti-Vasopressin Antibody detects level of Vasopressin & has been published & validated for use in IC, IH(P), RIA & WB. 主要应用 - Western Blotting
- Immunocytochemistry
应用说明 Immunohistochemistry: 1:5,000-1:10,000 (18-24 hour incubation) on formalin, Bouin's or Zamboni's fixed tissue. Will react on paraffin embedded tissue.
Immunocytochemistry: 1:1,000-1:200,000 (18-24 hour incubation) on fetal rat neurons.
Immunoblotting: 1:1,000
RIA: 1:30,000-1:750,000. Sensitivity of < 1 pg/mL.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Arginine vasopressin (Sigma) conjugated to thyroglobulin. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Vasopressin. Less than 1% cross-reactivity with oxytocin. 品种反应性 SheepHumanMouseRatRabbit 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000490.3
Entrez基因汇总 This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin II and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin II, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). 基因符号 - ADH
- AVP
- AVP-NPII
- VP
- AVRP
- ARVP
纯化方法 Unpurified UniProt编号 - P01185
UniProt汇总 FUNCTION: SwissProt: P01185 # Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels.
SIZE: 164 amino acids; 17325 Da
SUBCELLULAR LOCATION: Secreted.
DISEASE: SwissProt: P01185 # Defects in AVP are the cause of autosomal dominant neurohypophyseal diabetes insipidus (ADNDI) [MIM:125700]. ADNDI is characterized by persistent thirst, polydipsia and polyuria. The disease is transmitted in an autosomal dominant mode and appears to be largely if not completely penetrant. & Defects in AVP are the cause of autosomal recessive neurohypophyseal diabetes insipidus (ARNDI) [MIM:125700]. ARNDI is characterized by persistent thirst, polydipsia and polyuria. Most mutations are hypothesized to trigger neurodegeneration via disruption of preproAVP-NPII processing.
SIMILARITY: SwissProt: P01185 ## Belongs to the vasopressin/oxytocin family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 100 µL
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