merck millipore,默克密理愽
  • merck millipore,默克密理博,AB15518,Anti-Neuronal pentraxin 1 Antibody

  • merck millipore,默克密理博,AB15518,Anti-Neuronal pentraxin 1 Antibody

    产品名称：Anti-Neuronal pentraxin 1 Antibody
    产品型号：AB15518
    This Anti-Neuronal pentraxin 1 Antibody is validated for use in ELISA, WB, IH for the detection of Neuronal pentraxin 1.

    merck millipore,默克密理博,AB15518,Anti-Neuronal pentraxin 1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB15518,Anti-Neuronal pentraxin 1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MIHC, ELISA, WBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB15518
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Neuronal pentraxin 1 Antibody
    Alternate Names
    • NPX1
    背景信息 Neuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPX1(Neuronal Pentraxin 1) a 432aa protein in mouse and rat, 430aa in human (chr 17q25). It mediates the uptake of degraded synaptic material which could play an important role in synaptic remodeling, expressed in brain.
    产品信息
    格式 Affinity Purified
    演示 Liquid in PBS with 0.1% BSA.
    应用
    应用 This Anti-Neuronal pentraxin 1 Antibody is validated for use in ELISA, WB, IH for the detection of Neuronal pentraxin 1.
    主要应用
    • Immunohistochemistry
    • ELISA
    • Western Blotting
    应用说明 Western blot: 1-10 µg/mL using ECL.
    Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 µg/mL
    ELISA: 0.5-1 µg/mL using control peptide.
    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Synthetic peptide near the N-terminus of mouse NPX1
    宿主 Rabbit
    特异性 Neuronal pentraxin 1 (NPX1).
    品种反应性 Mouse
    Species Reactivity Note The immunogen sequence is 94% conserved in rat, and 82% in human NPX1.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_002522.2
    Entrez基因汇总 NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.
    基因符号
    • NP-I
    • NPTX1
    • DKFZp686J2446
    • MGC105123
    • NP1
    纯化方法 Immunoaffinity purified
    UniProt编号
    • Q15818
    UniProt汇总 FUNCTION: SwissProt: Q15818 # May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin (By similarity).
    COFACTOR: Binds 2 calcium ions per subunit (By similarity).
    SIZE: 432 amino acids; 47122 Da
    SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle (Potential).
    SIMILARITY: SwissProt: Q15818 ## Contains 1 pentaxin domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB15518,Anti-Neuronal pentraxin 1 Antibody

上一件merck millipore产品：merck millipore,默克密理博,SLGSV255F,Millex-GS，0.22 µm，混合纤维素酯，25 mm，带进口，环氧乙烷灭菌
下一件merck millipore产品：merck millipore,默克密理博,SF-456,IL-6; Human, Cyanine 5, RNA Detection Probe,SmartFlare


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