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品种反应性 主要应用 宿主 格式 抗体类型 R IHC Rb Purified Polyclonal Antibody 描述 产品目录编号 AB15467P 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-ARG3.1 Antibody Alternate Names - Growth factor ARC, Activity regulated cytoskeleton
- Growth factor ARC
背景信息 Arc/Arg3.1 is an immediate-early gene whose mRNA is rapidly transcribed and targeted to dendrites of neurons as they engage in information processing and storage. Arc/Arg3.1 is known to be required for durable forms of synaptic plasticity and learning. Arc/Arg3.1 has been shown to be expressed in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus. 产品信息 格式 Purified 演示 Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative. 应用 应用 Anti-ARG3.1 Antibody detects level of ARG3.1 & has been published & validated for use in IH. 主要应用 - Immunohistochemistry
应用说明 Immunohistochemistry: 1:200-1:1,000
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide corresponding to a region within the C-terminus of human ARG3.1 protein. 宿主 Rabbit 特异性 ARG3.1 [Growth factor ARC, Activity regulated cytoskeleton] 品种反应性 Rat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_015193.3
基因符号 - MYC
- ARC
- KIAA0278
- Arg3.1
- NOP
- NOL3
- ARC/ARG3.1
UniProt编号 - Q7LC44
UniProt汇总 FUNCTION: SwissProt: Q7LC44 # Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity).
SIZE: 396 amino acids; 45316 Da
SUBUNIT: Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2 (By similarity).
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton (By similarity). Endosome (By similarity). Acrosome (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Cell projection, dendrite (By similarity). Cell projection, dendritic spine (By similarity). Cell junction, synapse (By similarity). Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail (By similarity).
SIMILARITY: SwissProt: Q7LC44 ## Belongs to the ARC/ARG3.1 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability. 包装信息 数量 500 µg
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