merck millipore,默克密理博,IL017,Interleukin-6 Protein, Recombinant mouse

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merck millipore,默克密理博,IL017,Interleukin-6 Protein, Recombinant mouse
产品名称：Interleukin-6 Protein, Recombinant mouse
产品型号：IL017
The recombinant mouse Interleukin-6 protein (or IL-6 protein) is a potent lymphoid cell growth factor which affects B-lymphocytes, T-lymphocytes & hybridoma cells.

merck millipore,默克密理博,IL017,Interleukin-6 Protein, Recombinant mouse

产品介绍

merck millipore,默克密理博,IL017,Interleukin-6 Protein, Recombinant mouse

重要规格表

主要应用	品种	纯度
CULT	Mouse	Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of mouse IL-6.

描述
产品目录编号	IL017
品牌系列	Chemicon®
商名	Chemicon
描述	Interleukin-6 Protein, Recombinant mouse
概述	Interleukin-6 (IL-6) is a potent lymphoid cell growth factor which stimulates the growth and survivability of certain B-cells and T-cells. Mouse IL-6 is a 21.7 kDa protein containing 187 amino acid residues.
Alternate Names	IL-6

产品信息
演示	Sterile filtered, and then lyophilized with no additives.

应用
应用	The recombinant mouse Interleukin-6 protein (or IL-6 protein) is a potent lymphoid cell growth factor which affects B-lymphocytes, T-lymphocytes & hybridoma cells.
主要应用	Cell Culture
应用说明	For most in vitro applications, mouse IL-6 exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): B-cells, hybridoma cells.

生物信息
纯度	Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of mouse IL-6.
品种	Mouse
特异活性	The ED(50) was determined by the dose-dependent stimulation of the proliferation of IL-6 dependent mouse 7TD1 cells is <= 0.02 ng/mL, corresponding to a specific activity of >=5 x 10(E8) units/mg.
UniProt编号	P08505 P05231
UniProt汇总	FUNCTION: SwissProt: P05231 # IL-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants. SIZE: 212 amino acids; 23718 Da SUBCELLULAR LOCATION: Secreted. PTM: N- and O-glycosylated. DISEASE: SwissProt: P05231 # Genetic variations in IL6 are associated with susceptibility to systemic juvenile rheumatoid arthritis [MIM:604302]. Systemic juvenile rheumatoid arthritis is juvenile chronic arthritis associated with severe, debilitating, extraarticular features, and occasionally fatal complications. Despite medical treatment, many children still experience early joint destruction, necessitating surgical replacement. & At least 1 polymorphism in the IL6 gene renders HIV- infected men susceptible to Kaposi sarcoma [MIM:148000]. Kaposi sarcoma is a sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumor that results in multifocal purplish coloured papules or plaques that eventually form nodules. Most commonly seen in patients who suffer from AIDS. SIMILARITY: SwissProt: P05231 ## Belongs to the IL-6 superfamily.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20ºC for up to 12 months after date of receipt. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers and stored at 2-8°C for one week or -20°C for future use. Reconstituted mouse IL-6 should be stored in undiluted aliquots at -20°C for up to 6 months.

储存和货运信息

存储条件

The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20ºC for up to 12 months after date of receipt. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers and stored at 2-8°C for one week or -20°C for future use. Reconstituted mouse IL-6 should be stored in undiluted aliquots at -20°C for up to 6 months.