- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB15456 Replaces AB5947 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Brn4/POU3F4 Antibody Alternate Names - Brain-specific Homeobox/POU Domain Protein 4
背景信息 Brain 4 (Brn4/POU3F4) and Pax6 are POU-homeodomain and paired-homeodomain transcription factors, respectively, that are expressed in the brain and the glucagon-expressing cells in the pancreas. 产品信息 格式 Affinity Purified 控制 - Tested on embryonic mouse brain lysate
演示 Purified in PBS with 0.05% NaN3. 应用 应用 This Anti-Brn4/POU3F4 Antibody is validated for use in WB for the detection of Brn4/POU3F4. 主要应用 - Western Blotting
应用说明 Western blot: 0.5-5.0 μg/mL on extracts from e16 mouse brain lysate.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide 表位 aa. 72-88 (human) 宿主 Rabbit 特异性 Brn4/POU3F4 (Brain-specific Homeobox/POU Domain Protein 4). 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000307.2
基因符号 - Brn-4
- POU3F4
- BRN4
- OTF9
- BRAIN-4
- DFN3
- Brain-4
纯化方法 Immunoaffinity purified UniProt编号 - P49335
UniProt汇总 FUNCTION: SwissProt: P49335 # Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.
SIZE: 361 amino acids; 39427 Da
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Brain specific.
DISEASE: SwissProt: P49335 # Defects in POU3F4 are a cause of X-linked deafness type 3 (DFN3) [MIM:304400]. DFN3 is a mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.
SIMILARITY: SwissProt: P49335 ## Belongs to the POU transcription factor family. Class- 3 subfamily. & Contains 1 homeobox DNA-binding domain. & Contains 1 POU-specific domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MAB2237,Anti-Syntrophin Antibody, clone 1351
下一件merck millipore产品：merck millipore,默克密理博,SF-1799,MITF; Human, Cyanine 5 RNA Detection Probe,SmartFlare
相关产品
merck millipore,默克密理博,MAB1959,Anti-Integrin β1 Antibody, clone P5D2
merck millipore,默克密理博,23-036M,UbcH6 Protein, active, 250 µg
merck millipore,默克密理博,ABE347,Anti-NFκB p65 Antibody, CT
merck millipore,默克密理博,MAB5256,Anti-Neurofilament 200 kDa Antibody, clone NE14
merck millipore,默克密理博,MAB2237,Anti-Syntrophin Antibody, clone 1351
merck millipore,默克密理博,SF-1799,MITF; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,07-741,Anti-AS160 (Rab-GAP) Antibody
merck millipore,默克密理博,SCC008,ReNcell VM Human Neural Progenitor Cell LIne
merck millipore,默克密理博,AB1967,Anti-Integrin αIIb Antibody, cytoplasmic domain
merck millipore,默克密理博,SF-1369,CDH20; Human, Cyanine 3 RNA Detection Probe,SmartFlare