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  • merck millipore,默克密理博,AB10626,Anti-IL-1 β Antibody

  • merck millipore,默克密理博,AB10626,Anti-IL-1 β Antibody

    产品名称：Anti-IL-1 β Antibody
    产品型号：AB10626
    Anti-IL-1 β Antibody is an antibody against IL-1 β for use in WB.

    merck millipore,默克密理博,AB10626,Anti-IL-1 β Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB10626,Anti-IL-1 β Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    PoWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 AB10626
    Replaces 04-462; MABF22
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-IL-1 β Antibody
    背景信息 This antibody recognizes natural and recombinant swine IL-1 . either a 269 AA or a 271 AA (17 kDa) protein with no disulfide bonds. There are two distinct molecular forms of IL-1 (IL-1 and IL-1 ) derived from two different genes.
    产品信息
    格式 Purified
    演示 Rabbit polyclonal antibodies in phosphate buffered saline, pH 7.2.
    应用
    应用 Anti-IL-1 β Antibody is an antibody against IL-1 β for use in WB.
    主要应用
    • Western Blotting
    应用说明 This antibody is suitable for use in Western blot analysis at 0.5 - 2.0 ug/mL.
    This antibody is non-neutralizing when tested by proliferation assay.
    生物信息
    免疫原品种 Recombinant swine IL-1β.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes IL-1 Beta.
    品种反应性 Pig
    Species Reactivity Note Swine. Other species were not tested.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_000576.2
    Entrez基因汇总 The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
    基因符号
    • catabolin
    • IL1B
    • IL1F2
    • pro-interleukin-1-beta
    • IL1-BETA
    • Catabolin
    • IL-1
    • IL-1B
    纯化方法 Protein G purfied
    UniProt编号
    • P01584
    UniProt汇总 FUNCTION: SwissProt: P01584 # Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
    SIZE: 269 amino acids; 30748 Da
    SUBUNIT: Monomer.
    SUBCELLULAR LOCATION: Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
    DOMAIN: SwissProt: P01584 The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
    SIMILARITY: Belongs to the IL-1 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at -20°C in undiluted aliquots for 1 year from date of shipment.
    包装信息
    数量 500 µg

    merck millipore,默克密理博,AB10626,Anti-IL-1 β Antibody

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