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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB10324 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-CYP450 Pan 2C Antibody Alternate Names - cytochrome P450
产品信息 格式 Serum 演示 Raw Rabbit Serum with 0.1% Sodium Azide 应用 应用 This Anti-CYP450 Pan 2C Antibody is validated for use in WB for the detection of CYP450 Pan 2C. 主要应用 - Western Blotting
生物信息 免疫原品种 Recombinant CYP450 2C19 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000769.1
Entrez基因汇总 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. 基因符号 - P450C2C
- CYP2C19
- CYPIIC19
- CYP2C
- OTTHUMP00000059588
- P450-254C
- CYPIIC17
- CPCJ
- P450-11A
- P450IIC19
纯化方法 Serum UniProt编号 - P33261
UniProt汇总 FUNCTION: SwissProt: P33261 # Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
SIZE: 490 amino acids; 55931 Da
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
SIMILARITY: SwissProt: P33261 ## Belongs to the cytochrome P450 family.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at 2-8°C from date of shipment 包装信息 数量 100 µL
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