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经验配方 CAS号 C₄₆H₅₈N₄O₉ · H₂SO₄ 143-67-9 描述 概述 Antitumor alkaloid drug. Induces apoptosis in cultured hepatocytes and human lymphoma cells. Affects interaction of tubulin with microtubule-associated proteins, specifically Tau and MAP2. Depolymerizes microtubules. Increases frequency of micronucleated erythrocytes. 产品目录编号 677175 品牌系列 Calbiochem®
参考 参考 Tanaka, E., et al. 1995. J. Cell. Biol. 128, 139.
Boscoboinik, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 374.
Smith, C.D., et al. 1994. Cancer Lett. 79, 213.
Smith, C.D., et al. 1994. Cancer Res. 54, 3779.
Tsukidate, K., et al. 1993. Am. J. Pathol. 143, 198.
Jagetia, G.C., and Jacob, P.S. 1992. Mutat. Res. 280, 87.
Jordan, M.A., et al. 1992. J. Cell Sci. 102, 401.
Prasad, V., et al. 1992. J. Protein Chem. 11, 509.产品信息 CAS号 143-67-9 具有ATP竞争性 N 形式 White crystalline solid Hill配方 C₄₆H₅₈N₄O₉ · H₂SO₄ 化学配方 C₄₆H₅₈N₄O₉ · H₂SO₄ Molar Mass 909.1 可逆 N 结构配方图像 生物信息 主靶 Interaction of tubulin with microtubule-associated proteins, specifically Tau and MAP2 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O GHS安全信息 RTECS YY8400000 安全信息 R相 R: 22-37/38-61-41
Harmful if swallowed.
Irritating to respiratory system and skin.
May cause harm to the unborn child.
Risk of serious damage to eyes.S相 S: 22-26-36/37/39-45
Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful & Carcinogenic / Teratogenic
储存 +2°C to +8°C
避光 Protect from light
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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