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merck millipore,默克密理博,205530,CA-074 - Calbiochem
产品名称：CA-074 - Calbiochem
产品型号：205530
CA-074, also referenced under CAS 134448-10-5, modulates the biological activity of cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
merck millipore,默克密理博,205530,CA-074 - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₈H₂₉N₃O₆ 描述 概述 An epoxysuccinyl peptide that acts as a potent, irreversible, and specific inhibitor of cathepsin B (IC50 = 2.24 nM for rat liver cathepsin B). Reduces ischemia-induced neuronal death. Exhibits lower membrane permeability when compared to CA-074 Me (Cat. No. 205531). 产品目录编号 205530 品牌系列 Calbiochem®
同义词 Cathepsin B Inhibitor III, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline 参考 参考 Chan, V.J., et al. 1999. Biochem. J. 340, 113.
Tsuchiya, K., et al. 1999. Exp. Neurol. 155, 187.
Yamamoto, A., et al. 1997. J. Biochem. 121, 974.
Inubushi, T., et al. 1994. J. Biochem. 116, 282.
Murata, M., et al. 1991. FEBS Lett. 280, 307.
Towatari, T., et al. 1991. FEBS Lett. 280, 311.产品信息 具有ATP竞争性 N 形式 Colorless or white solid Hill配方 C₁₈H₂₉N₃O₆ 化学配方 C₁₈H₂₉N₃O₆ Molar Mass 383.4 可逆 N 结构配方图像 生物信息 主靶 cathepsin B 主靶IC50 2.24 nM for rat liver cathepsin B 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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