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merck millipore,默克密理博,616520,TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem
产品名称:TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem
产品型号:616520
The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications.
merck millipore,默克密理博,616520,TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₄H₂₂Cl₂N2O₂S 946387-07-1 描述 概述 A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4α-PDD- (Cat. No. 524394) stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9 µM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- (Cat. No. 211275) activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30 µM). 产品目录编号 616520 品牌系列 Calbiochem®
同义词 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734 参考 参考 Vincent, F., et al. 2009. Biochem. Biophys. Res. Commun. 389, 490. 产品信息 CAS号 946387-07-1 形式 Yellow solid Hill配方 C₁₄H₂₂Cl₂N2O₂S 化学配方 C₁₄H₂₂Cl₂N2O₂S Molar Mass 353.3 结构配方图像 生物信息 纯度 ≥95% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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