• merck millipore,默克密理博,616520,TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem
  • merck millipore,默克密理博,616520,TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem

    产品名称:TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem
    产品型号:616520
    The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications.

    merck millipore,默克密理博,616520,TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,616520,TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₄H₂₂Cl₂N2O₂S946387-07-1
    描述
    概述 A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4α-PDD- (Cat. No. 524394) stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9 µM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- (Cat. No. 211275) activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30 µM).
    产品目录编号 616520
    品牌系列 Calbiochem®
    同义词 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734
    参考
    参考 Vincent, F., et al. 2009. Biochem. Biophys. Res. Commun. 389, 490.
    产品信息
    CAS号 946387-07-1
    形式 Yellow solid
    Hill配方 C₁₄H₂₂Cl₂N2O₂S
    化学配方 C₁₄H₂₂Cl₂N2O₂S
    Molar Mass 353.3
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,616520,TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem

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