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merck millipore,默克密理博,613570,TIRAP Inhibitor Peptide, Cell-Permeable - Calbiochem
产品名称：TIRAP Inhibitor Peptide, Cell-Permeable - Calbiochem
产品型号：613570
The TIRAP Inhibitor Peptide, Cell-Permeable blocks LPS-, but not CpG-induced NF-κB activation. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
merck millipore,默克密理博,613570,TIRAP Inhibitor Peptide, Cell-Permeable - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₆₃H₂₆₈N₅₂O₃₈S 描述 概述 A cell-permeable synthetic peptide containing mouse TIRAP138-151 fused to the Drosophila Antennapedia sequence. Specifically inhibits LPS-, but not CpG-induced NF-κB activation, PKR phosphorylation, and JNK phosphorylation in RAW.κB cells at ~40 µM. Also reported to block IκBα degradation. 产品目录编号 613570 品牌系列 Calbiochem®
同义词 Ant-Tirap138-151, TIRAP Peptide, Mal Peptide, MyD88-Adapter-Like Peptide, Toll-interleukin 1 Receptor (TIR) domain-containing Adapter Protein Peptide, (RQIKIWFNRRMKWKKLQLRDAAPGGAIVS) 参考 参考 Toshchakov, V., et al. 2002. Nat. Immunol. 3, 392.
Fitzgerald, K.A., et al. 2001. Nature 413, 78.
Henneke, P. and Golenbock, D.T. 2001. Nat. Immunol. 2, 828.
Horng, T., et al. 2001. Nat. Immunol. 2, 835.产品信息 具有ATP竞争性 N 形式 White lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₆₃H₂₆₈N₅₂O₃₈S 化学配方 C₁₆₃H₂₆₈N₅₂O₃₈S Molar Mass 3596.3 吸湿 Hygroscopic
肽序列 H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Leu-Gln-Leu-Arg-Asp-Ala-Ala-Pro-Gly-Gly-Ala-Ile-Val-Ser-OH 可逆 N 生物信息 主靶 LPS-induced NF-κB activation, PKR phosphorylation, and JNK phosphorylation in RAW.kB cells 纯度 ≥97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 肽序列 H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Leu-Gln-Leu-Arg-Asp-Ala-Ala-Pro-Gly-Gly-Ala-Ile-Val-Ser-OH 储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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