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描述 概述 Native TIMP-1 from human granulocyte. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Binds to pro-MMP-9 and MMP-9 via their C-terminal domains. 产品目录编号 612080 品牌系列 Calbiochem®
同义词 Tissue Inhibitor of Metalloproteinase-1 参考 参考 Kolkenbrock, H., et al. 1996. Biol. Chem. 377, 529.
Kolkenbrock, H., et al. 1995. Biol. Chem. Hoppe Seyler 376, 495.产品信息 具有ATP竞争性 N 形式 Liquid 配方 In 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ® 35 Detergent, 0.05% NaN₃, pH 7.0. Molar Mass 28000 可逆 N 生物信息 主靶 MMP activity 纯度 ≥90% by SDS-PAGE 来源 Prepared from stimulated neutrophils that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 浓缩标签 Please refer to vial label for lot-specific concentration
理化信息 细胞可渗透 N 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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