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merck millipore,默克密理博,658550,AG 1295 - CAS 71897-07-9 - Calbiochem
产品名称：AG 1295 - CAS 71897-07-9 - Calbiochem
产品型号：658550
A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC₅₀ = 500 nM) and PDGF-dependent DNA synthesis (IC₅₀ = 2.5 µM) in Swis More>>
merck millipore,默克密理博,658550,AG 1295 - CAS 71897-07-9 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₆H₁₄N₂ 71897-07-9 描述 概述 A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 µM) in Swiss/3T3 cells. Has no effect on EGF receptor autophosphorylation and shows only a weak effect on EGF- or insulin-stimulated DNA synthesis. A potent blocker of smooth muscle cell proliferation. 产品目录编号 658550 品牌系列 Calbiochem®
同义词 6,7-Dimethyl-2-phenylquinoxaline 参考 参考 Banai, S., et al. 1998. Circulation 97, 1960.
Levitzki, A., and Gazit, A. 1995. Science 267, 1782.
Kovalenko, M., et al. 1994. Cancer Res. 54, 6106.产品信息 CAS号 71897-07-9 具有ATP竞争性 Y 形式 White solid Hill配方 C₁₆H₁₄N₂ 化学配方 C₁₆H₁₄N₂ Molar Mass 234.3 可逆 Y 结构配方图像 生物信息 主靶 PDGFR kinase 主靶IC50 500 nM against PDGFR kinase 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or CH₂Cl₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
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