merck millipore,默克密理愽
  • merck millipore,默克密理博,579052,TAPI-2 - CAS 187034-31-7 - Calbiochem

  • merck millipore,默克密理博,579052,TAPI-2 - CAS 187034-31-7 - Calbiochem

    产品名称：TAPI-2 - CAS 187034-31-7 - Calbiochem
    产品型号：579052
    A hydroxamate-based inhibitor of MMPs and TACE.

    merck millipore,默克密理博,579052,TAPI-2 - CAS 187034-31-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,579052,TAPI-2 - CAS 187034-31-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₃₇N₅O₅187034-31-7
    描述
    概述 A hydroxamate-based inhibitor of MMPs and TACE. Inhibits the activation-induced shedding of L-selectin from neutrophils, eosinophils, and lymphocytes, as well as phenylarsine oxide (PAO)-induced shedding in neutrophils. Also acts as a weak inhibitor of angiotensin converting enzyme (IC50 = 18 µM). Also available as a 10 mM solution in H2O (Cat. No. 509612).
    产品目录编号 579052
    品牌系列 Calbiochem®
    同义词 N-(R)-[2-(Hydroxyaminocarbonyl)methyl]-4-methylpentanoyl-L-t-butyl-alanyl-L-alanine, 2-aminoethyl Amide, TNF-α Protease Inhibitor-2
    参考
    参考 Bennett, T.A., et al. 2000. J. Immunol. 164, 4120.
    Fiorucci, S., et al. 1998. Aliment. Pharmacol. Ther. 12, 1139.
    Hooper, N.M., et al. 1997. Biochem. J. 321, 265.
    Parvathy, S., et al. 1997. Biochem. J. 327, 37.
    Arribas, J., et al. 1996. J. Biol. Chem. 271, 11376.
    产品信息
    CAS号 187034-31-7
    具有ATP竞争性 N
    声明 Manufactured exclusively by Peptides International, Louisville, Kentucky, USA.
    形式 White solid
    Hill配方 C₁₉H₃₇N₅O₅
    化学配方 C₁₉H₃₇N₅O₅
    Molar Mass 415.5
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 MMPs
    主靶IC50 18 µM against angiotensin converting enzyme
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 EtOH or H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,579052,TAPI-2 - CAS 187034-31-7 - Calbiochem

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