merck millipore,默克密理愽
  • merck millipore,默克密理博,573103,STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem

  • merck millipore,默克密理博,573103,STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem

    产品名称：STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem
    产品型号：573103
    The STAT3 Inhibitor VII, also referenced under CAS 1041438-68-9, controls the biological activity of STAT3.

    merck millipore,默克密理博,573103,STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,573103,STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₇F₇N₂O₃1041438-68-9
    描述
    概述 A cell-permeable dihydroquinoline compound that potently and specifically inhibits cellular JAK1/JAK2/TYK2/STAT3 activation (IC50 against U266 constitutive STAT3 Y705 phosphorylation =170 nM) as well as the transcription of STAT3 target genes, while exhibiting little effects against pathways involved in Akt/mTOR, Erk1/2, or STAT5 activation. Since the inhibitor does not affect JAK1/2/3 kinase activity, its cellular target(s) appears to be upstream of JAKs.
    产品目录编号 573103
    品牌系列 Calbiochem®
    同义词 Ethyl-1-(4-cyano-2,3,5,6-tetrafluorophenyl)-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
    参考
    参考 Xu, J., et al. 2008. J. Med. Chem. 51, 4115.
    产品信息
    CAS号 1041438-68-9
    形式 Light orange solid
    Hill配方 C₁₉H₇F₇N₂O₃
    化学配方 C₁₉H₇F₇N₂O₃
    Molar Mass 444.3
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,573103,STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,448103,Met/Flt-3/VEGFR2 Tyrosine Kinase Inhibitor - CAS 888719-03-7 - Calbiochem


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