• merck millipore,默克密理博,567727,D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem
  • merck millipore,默克密理博,567727,D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem

    产品名称:D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem
    产品型号:567727
    A putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway.

    merck millipore,默克密理博,567727,D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,567727,D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₃₈NO₅P26993-30-6
    描述
    概述 A putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway. Activates phospholipase D (PLD) and inhibits chemotactic motility and invasiveness of tumor cells. Also stimulates growth of quiescent Swiss/3T3 fibroblasts. Inhibits activation of caspases that cleave PARP and lamins during Fas- and ceramide-mediated apoptosis.
    产品目录编号 567727
    品牌系列 Calbiochem®
    参考
    参考 Cuvillier, O., et al. 1998. J. Biol. Chem. 273, 2910.
    Mattie, M., et al. 1994. J. Biol. Chem. 269, 3181.
    Olivera, A. and Spiegel, S. 1993. Nature 365, 557.
    Desai, N.N., et al. 1992. J. Biol. Chem. 267, 23122.
    Sadahira, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 9686.
    产品信息
    CAS号 26993-30-6
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₈H₃₈NO₅P
    化学配方 C₁₈H₃₈NO₅P
    Molar Mass 379.5
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 Mobilizes calcium from intracellular stores
    纯度 ≥95% by TLC
    理化信息
    细胞可渗透 N
    溶解度 Warm MeOH
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and evaporate under a stream of nitrogen. Store at -20°C. Prior to use, dissolve in 4 mg/ml BSA solution with vortexing. Stock solutions are stable for up to 2 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,567727,D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem

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