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纯度 ≥90% by SDS-PAGE 描述 概述 Recombinant, mouse sclerostin (SOST) consisting of amino acids 24-211, expressed in NS0-derived murine myeloma cells with an N-terminal His•Tag®. SOST is expressed by osteoclasts in developing bones of mouse embryos and acts as a negative regulator of bone formation through repression of BMP-induced osteogenesis. 产品目录编号 567693 品牌系列 Calbiochem®
参考 参考 Kusu, N. et al. 2003. J. Biol. Chem. 278, 24113.
Balemans, W. et al. 2001. Hum. Mol. Genet. 10 537.
Brunkow, M.E. et al. 2001. Am. J. Hum. Genet. 68, 577.产品信息 形式 Solid 配方 Lyophilized from 0.2 µm filter-sterilized PBS, BSA. 生物信息 生物活性 Inhibition Assay: Inhibits hBMP-6-induced alkaline phosphatase by 50-80% in MC3T3-E1 mouse osteoblastic cells when used at a concentration of 30 µg/ml. 纯度 ≥90% by SDS-PAGE 理化信息 污染物 Endotoxin: <1.0 EU/µg protein 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
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