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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB4350 描述 Anti-PRDM14 Antibody Alternate Names - PR domain-containing protein 14
- PR domain zinc finger protein 14
背景信息 PR domain proteins (PRDMs) have been associated with many types of human cancers. PRDM14 was found to be up-regulated in breast cancer cells. The expression of PRDM14 to breast cancer cells actually increased cell proliferation and decreased the effect of chemotherapeutic drugs, while down-regulation of PRDM14 did the opposite. In addition to breast cancer, PRDM14 has recently been linked to non-small cell lung cancer development. PRDM14 also seems to play a role in the preservation of the self-renewal of human embryonic stem cells and transcriptional regulation. 产品信息 格式 Affinity Purified 控制 - Human lung tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl and 0.05% sodium azide. 应用 应用 This Anti-PRDM14 Antibody is validated for use in WB for the detection of PRDM14. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to the N-terminus of human PRDM14. 表位 N-terminus 宿主 Rabbit 特异性 This antibody recognizes the N-terminus of PRDM14. 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_078780
Entrez基因汇总 Summary: The PR domain is a protein-protein interaction module of about 100 amino acids. PR domain-containing proteins, such as PRDM14, are often involved in transcriptional regulation (Jiang and Huang, 2000 [PubMed 10668202]).[supplied by OMIM]. 基因符号 - PRDM14
纯化方法 Affinity Purified UniProt编号 - Q9GZV8
UniProt汇总 FUNCTION: May be involved in transcriptional regulation.
SUBCELLULAR LOCATION: Nucleus (potential).
SEQUENCE SIMILARITIES: Contains 6 C2H2-type zinc fingers. Contains 1 SET domain.产品使用声明 质量保证 Evaluated by Western Blot in human lung tissue lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected PRDM14 in 10 µg of human lung tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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