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经验配方 CAS号 C₁₀H₁₁O₂Na 1716-12-7 描述 概述 A novel anti-neoplastic agent and transcriptional regulator. Also acts as an inducer of tumor cytostasis and differentiation. Increases fetal hemoglobin production in vitro and in vivo. 产品目录编号 567616 品牌系列 Calbiochem®
同义词 SPB, PBNa, 4PBA, 4-Phenylbutyrate, Na, BDK Inhibitor I, BCKD Kinase Inhibitor I, Branched-Chain α-Ketoacid Dehydrogenase Kinase Inhibitor I 参考 参考 Tso, S.C., et al. 2013. Proc. Natl. Acad. Sci. USA 110, 9728.
Ozcan, U., et al. 2006. Science 313, 1137.
Carducci, M.A., et al. 2001. Clin. Cancer Res. 7, 3047.
Rubenstein, R.C. and Zeitlin, P.L. 2000. Am.J. Physiol. Cell. Physiol. 278, C259.
Lea, M.A., et al. 1999. Anticancer Res. 19, 1971.
Miller, A.C., et al. 1997. Int. J. Radiat. Biol. 72, 211.
Rubenstein, R.C., et al. 1997. J. Clin. Invest. 100, 2457.
Pineau, T., et al. 1996. Biochem. Pharmacol. 52, 659.
Collins, A.F., et al. 1995. Blood 85, 43.
Lea, M.A., et al. 1995. Anticancer Res. 15, 879.
Figg, W.D., et al. 1994. Anticancer Drugs 5, 336.
Liu, L., et al. 1994. J. Invest. Dermatol. 103, 335.产品信息 CAS号 1716-12-7 具有ATP竞争性 N 形式 White to slightly yellow solid Hill配方 C₁₀H₁₁O₂Na 化学配方 C₁₀H₁₁O₂Na Molar Mass 186.2 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 Anti-neoplastic agent 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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