merck millipore,默克密理愽
  • merck millipore,默克密理博,566313,SIRT1 Activator II - CAS 374922-43-7 - Calbiochem

  • merck millipore,默克密理博,566313,SIRT1 Activator II - CAS 374922-43-7 - Calbiochem

    产品名称：SIRT1 Activator II - CAS 374922-43-7 - Calbiochem
    产品型号：566313
    The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications.

    merck millipore,默克密理博,566313,SIRT1 Activator II - CAS 374922-43-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,566313,SIRT1 Activator II - CAS 374922-43-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₂H₁₅FN₄O₂S374922-43-7
    描述
    概述 A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10 µM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-α release in THP-1 cells by ~10-fold more potent than resveratrol (Cat. No. 554325).
    产品目录编号 566313
    品牌系列 Calbiochem®
    同义词 3-(Benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[4,5-b]quinoxalin-2-amine , SIRT1 Activator II
    参考
    参考 Lavu, S., et al. 2008. Nat. Rev. Drug Discov. 7, 841.
    Nayagam, V.M., et al. 2006. J. Biomol. Screen. 11, 959.
    产品信息
    CAS号 374922-43-7
    形式 Off-white powder
    Hill配方 C₂₂H₁₅FN₄O₂S
    化学配方 C₂₂H₁₅FN₄O₂S
    Molar Mass 418.4
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,566313,SIRT1 Activator II - CAS 374922-43-7 - Calbiochem

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