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merck millipore,默克密理博,402086,Indirubin-3ʹ-monoxime, 5-Iodo- - CAS 331467-03-9 - Calbiochem
产品名称:Indirubin-3ʹ-monoxime, 5-Iodo- - CAS 331467-03-9 - Calbiochem
产品型号:402086
A highly potent cell-permeable and reversible inhibitor of glycogen synthase kinase-3β (GSK-3β; IC₅₀ = 9 nM).
merck millipore,默克密理博,402086,Indirubin-3ʹ-monoxime, 5-Iodo- - CAS 331467-03-9 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₆H₁₀IN₃O₂ 331467-03-9 描述 概述 A highly potent cell-permeable and reversible inhibitor of glycogen synthase kinase-3β (GSK-3β; IC50 = 9 nM). Also inhibits Cdk1 (IC50 = 25 nM) and Cdk5 (IC50 = 20 nM) activities. Acts by binding to the ATP-binding pocket of these enzymes. 产品目录编号 402086 品牌系列 Calbiochem®
参考 参考 Leclerc, S., et al. 2001. J. Biol. Chem. 276, 251.
Hoessel, R., et al. 1999. Nat. Cell Biol. 1, 60.产品信息 CAS号 331467-03-9 具有ATP竞争性 Y 形式 Dark red solid Hill配方 C₁₆H₁₀IN₃O₂ 化学配方 C₁₆H₁₀IN₃O₂ Molar Mass 403.2 可逆 Y 结构配方图像 生物信息 主靶 Gsk-3β 主靶IC50 9 nM against GSK-3β 纯度 ≥97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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