merck millipore,默克密理博,ABC156,Anti-BAG family molecular chaperone regulator 3 (BAG3) Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABC156
描述	Anti-BAG family molecular chaperone regulator 3 (BAG3) Antibody
Alternate Names	Docking protein CAIR-1 Bcl-2-associated athanogene 3 Bcl-2-binding protein Bis
背景信息	Bcl2-associated athanogene 3 (BAG3), also known as CAIR-1 or Bis, belongs to a family of six evolutionarily conserved co-chaperone proteins that contain a characteristic C-terminal BAG domain. In most cell types, BAG3 is localized to the cytoplasm, where it regulates the heat shock protein 70 chaperone. BAG3 is activated in response to stressful stimuli, and plays a critical role in modulating multiple cellular processes, including apoptosis, autophagy, embryonic development, and actin rearrangement. Abnormal expression of BAG3 results cardiomyopathy dilated type 1HH.

产品信息
格式	Affinity Purified
控制	DU145 cell lysate
演示	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect BAG family molecular chaperone regulator 3 (BAG3) using this Anti-BAG family molecular chaperone regulator 3 (BAG3) Antibody validated for use in Western Blotting, IHC(P).
主要应用	Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:500-1:1,000 dilution from a representative lot detected BAG3 in human cardiac and renal tissues.

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to human BAG3.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Human
Species Reactivity Note	Demonstrated to react with Human. Predicted to react with Mouse, Rat, Canine, and Rhesus Macaque based on 100% sequence homology.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_004272
基因符号	BIS BAG3
纯化方法	Affinity purified
UniProt编号	O95817

产品使用声明
质量保证	Evaluated by Western Blot in DU145 cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected BAG3 in 10 µg of DU145 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABC156,Anti-BAG family molecular chaperone regulator 3 (BAG3) Antibody

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