• merck millipore,默克密理博,474780,MG-115 - CAS 133407-86-0 - Calbiochem
  • merck millipore,默克密理博,474780,MG-115 - CAS 133407-86-0 - Calbiochem

    产品名称:MG-115 - CAS 133407-86-0 - Calbiochem
    产品型号:474780
    Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively).

    merck millipore,默克密理博,474780,MG-115 - CAS 133407-86-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,474780,MG-115 - CAS 133407-86-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₅H₃₉N₃O₅133407-86-0
    描述
    概述 Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively). Specifically inhibits the chymotrypsin-like activity of the proteasome and induces apoptosis in Rat-1 and PC12 cells.
    产品目录编号 474780
    品牌系列 Calbiochem®
    同义词 Carbobenzoxy-L-leucyl-L-leucyl-L-norvalinal, Z-LL-Nva-CHO, Proteasome Inhibitor XII
    参考
    参考 Lopes, U.G., et al. 1997. J. Biol. Chem. 272, 12893.
    Lee, D.H., and Goldberg, A.L. 1996. J. Biol. Chem. 271, 27280.
    Palombella, V.J., et al. 1994. Cell 78, 773. Rock, K.L., et al. 1994. Cell 78, 761.
    Vinitsky, A., et al. 1992. Biochemistry 31, 9421.
    产品信息
    CAS号 133407-86-0
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₅H₃₉N₃O₅
    化学配方 C₂₅H₃₉N₃O₅
    Molar Mass 461.6
    肽序列 Z-Leu-Leu-Nva-CHO
    可逆 Y
    结构配方图像
    生物信息
    主靶 20S proteasome
    主靶Ki 21 nM and 35 nM for 20S and 26S proteasome, respectively
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    肽序列 Z-Leu-Leu-Nva-CHO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,474780,MG-115 - CAS 133407-86-0 - Calbiochem

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