merck millipore,默克密理愽
  • merck millipore,默克密理博,553513,Rac Inhibitor III, EHop-016 - CAS 1380432-32-5 - Calbiochem

  • merck millipore,默克密理博,553513,Rac Inhibitor III, EHop-016 - CAS 1380432-32-5 - Calbiochem

    产品名称：Rac Inhibitor III, EHop-016 - CAS 1380432-32-5 - Calbiochem
    产品型号：553513
    The Rac Inhibitor III, EHop-016 controls the biological activity of Rac. This small molecule/inhibitor is primarily used for Membrane applications.

    merck millipore,默克密理博,553513,Rac Inhibitor III, EHop-016 - CAS 1380432-32-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,553513,Rac Inhibitor III, EHop-016 - CAS 1380432-32-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₅H₃₀N₆O1380432-32-5
    描述
    概述 A cell-permeable NSC23766 (Cat. No. 553502) analog that is more selective against Rac interaction with Vav2 (by 45% blockage at 4 µM) than Tiam (35% blockage at 50 µM) and ~100-times more potent than NSC23766 in suppressing Rac1-GTP level in MDA-MB-435 (IC50 = 1.1 vs. 95 µM, respectively) cultures. Effectively inhibits PAK Thr423 phosphorylation (IC50 <2 µM), while reducing Cdc42-GTP level only at higher concentrations (by 18% at 5 µM), in MDA-MB-435 cultures.
    产品目录编号 553513
    品牌系列 Calbiochem®
    同义词 N⁴-(9-Ethyl-9H-carbazol-3-yl)-N²-(3-morpholin-4-yl-propyl)-pyrimidine-2,4-diamine
    参考
    参考 Montalvo-Ortiz, B.L., et al. 2012. J. Biol. Chem. 287, 13228.
    产品信息
    CAS号 1380432-32-5
    形式 Pale yellow powder
    Hill配方 C₂₅H₃₀N₆O
    化学配方 C₂₅H₃₀N₆O
    Molar Mass 430.6
    结构配方图像
    生物信息
    纯度 ≥96% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,553513,Rac Inhibitor III, EHop-016 - CAS 1380432-32-5 - Calbiochem

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