• merck millipore,默克密理博,553008,Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem
  • merck millipore,默克密理博,553008,Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem

    产品名称:Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem
    产品型号:553008
    The Raf1 Kinase Inhibitor I, also referenced under CAS 220904-83-6, controls the biological activity of Raf1 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphoryla More>>

    merck millipore,默克密理博,553008,Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,553008,Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₈Br₂INO₂220904-83-6
    描述
    概述 A potent, cell-permeable, reversible, and ATP-competitive cRAF1 kinase inhibitor (IC50 = 9 nM). Shows ≥100-fold selectivity for Raf kinase versus Cdk1, Cdk2, c-Src, ERK2, MEK, p38, Tie2, VEGFR2, and c-Fms. Predicted broad spectrum antitumor agents. A 10 mM (500 µg/96 µl) solution of Raf1 Inhibitor I (Cat. No. 553003) in DMSO is also available.
    产品目录编号 553008
    品牌系列 Calbiochem®
    同义词 5-Iodo-3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-2-indolinone, GW 5074
    参考
    参考 Lackey, K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 223.
    产品信息
    CAS号 220904-83-6
    具有ATP竞争性 Y
    形式 Dark orange solid
    Hill配方 C₁₅H₈Br₂INO₂
    化学配方 C₁₅H₈Br₂INO₂
    Molar Mass 520.9
    可逆 Y
    结构配方图像
    生物信息
    主靶 CRAFI kinase
    主靶IC50 9 nM
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

    From Catalog:
    Desc. Field- added "Predicted broad spectrum antitumor agents.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,553008,Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,219399,Cathepsin D Substrate I - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,AG916-500UG,β Amyloid 1-42, aβ, scrambled, TFA, recombinant E. coli



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