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merck millipore,默克密理博,553008,Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem
产品名称:Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem
产品型号:553008
The Raf1 Kinase Inhibitor I, also referenced under CAS 220904-83-6, controls the biological activity of Raf1 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphoryla More>>
merck millipore,默克密理博,553008,Raf1 Kinase Inhibitor I - CAS 220904-83-6 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₅H₈Br₂INO₂ 220904-83-6 描述 概述 A potent, cell-permeable, reversible, and ATP-competitive cRAF1 kinase inhibitor (IC50 = 9 nM). Shows ≥100-fold selectivity for Raf kinase versus Cdk1, Cdk2, c-Src, ERK2, MEK, p38, Tie2, VEGFR2, and c-Fms. Predicted broad spectrum antitumor agents. A 10 mM (500 µg/96 µl) solution of Raf1 Inhibitor I (Cat. No. 553003) in DMSO is also available. 产品目录编号 553008 品牌系列 Calbiochem®
同义词 5-Iodo-3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-2-indolinone, GW 5074 参考 参考 Lackey, K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 223. 产品信息 CAS号 220904-83-6 具有ATP竞争性 Y 形式 Dark orange solid Hill配方 C₁₅H₈Br₂INO₂ 化学配方 C₁₅H₈Br₂INO₂ Molar Mass 520.9 可逆 Y 结构配方图像 生物信息 主靶 CRAFI kinase 主靶IC50 9 nM 纯度 ≥97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
From Catalog:
Desc. Field- added "Predicted broad spectrum antitumor agents.包装信息 惰性气体下包装 Packaged under inert gas
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