merck millipore,默克密理愽
  • merck millipore,默克密理博,551590,Quercetagetin - CAS 90-18-6 - Calbiochem

  • merck millipore,默克密理博,551590,Quercetagetin - CAS 90-18-6 - Calbiochem

    产品名称：Quercetagetin - CAS 90-18-6 - Calbiochem
    产品型号：551590
    A cell-permeable flavanol compound that acts a potent, ATP-competitive, and reversible inhibitor of PIM1 kinase (IC₅₀ = 340 nM).

    merck millipore,默克密理博,551590,Quercetagetin - CAS 90-18-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,551590,Quercetagetin - CAS 90-18-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₁₀O₈90-18-6
    描述
    概述 A cell-permeable flavanol compound that acts a potent, ATP-competitive, and reversible inhibitor of PIM1 kinase (IC50 = 340 nM). Exhibits ≥7-fold selectivity over 8 other kinases tested, including PIM2 (IC50 = 3.45 µM), and little activity toward c-Abl even at concentrations as high as 200 µM. Inhibits cellular BAD phosphorylation (IC50 = 5.5 µM) and induces growth arrest (ED50 = 3.8 µM) in PIM1-expressing RWPE2 cells.
    产品目录编号 551590
    品牌系列 Calbiochem®
    同义词 3,3ʹ,4ʹ,5,6,7-Hexahydroxyflavone
    参考
    参考 Holder, S., et al. 2007. Mol. Cancer Ther. 6, 163.
    产品信息
    CAS号 90-18-6
    具有ATP竞争性 Y
    形式 Green solid
    Hill配方 C₁₅H₁₀O₈
    化学配方 C₁₅H₁₀O₈
    Molar Mass 318.3
    可逆 Y
    结构配方图像
    生物信息
    主靶 PIM1 kinase
    主靶IC50 340 nM against PIM1 kinase
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Toxic & Carcinogenic / Teratogenic
    有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,551590,Quercetagetin - CAS 90-18-6 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,DR1056,Anti-SQSTM1 Mouse pAb


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