merck millipore,默克密理博,540500,Purvalanol A - CAS 212844-53-6

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Merck Millipore 默克密理愽

merck millipore,默克密理博,540500,Purvalanol A - CAS 212844-53-6 - Calbiochem

经验配方	CAS号
C₁₉H₂₅ClN₆O	212844-53-6

描述
概述	A potent, cell-permeable, reversible, and selective inhibitor of cyclin-dependent kinases (Cdks; IC₅₀ = 4 nM for Cdc2/cyclin B; IC₅₀ = 70 nM for Cdk2/cyclin A; IC₅₀ = 35 nM for Cdk2/cyclin E; and IC₅₀ = 75 nM for Cdk5/p35).
产品目录编号	540500
品牌系列	Calbiochem®
同义词	2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropyl-purine

参考
参考	Gray, N.S., et al. 1998. Science 281, 533.

产品信息
CAS号	212844-53-6
具有ATP竞争性	N
声明	Sold under license of U.S. Patents 6,617,331 and 6,803,371.
形式	Off-white solid
Hill配方	C₁₉H₂₅ClN₆O
化学配方	C₁₉H₂₅ClN₆O
Molar Mass	388.9
可逆	Y
结构配方图像

生物信息
主靶	Cdc2/cyclin B
主靶IC₅₀	4 nM for Cdc2/cyclin B; 70 nM for Cdk2/cyclin A; 35 nM for Cdk2/cyclin E; 75 nM for Cdk5/p35
纯度	≥97% by HPLC

理化信息
细胞可渗透	Y
溶解度	DMSO

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
无需冷冻	No
特殊指南	Following initial thaw, aliquot and freeze (-20°C).

包装信息
惰性气体下包装	Packaged under inert gas

merck millipore,默克密理博,540500,Purvalanol A - CAS 212844-53-6 - Calbiochem

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