merck millipore,默克密理愽
  • merck millipore,默克密理博,539652,PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem

  • merck millipore,默克密理博,539652,PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem

    产品名称：PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem
    产品型号：539652
    The PKCβII/EGFR Inhibitor, also referenced under CAS 145915-60-2, controls the biological activity of PKCβII/EGFR. This small molecule/inhibitor is primarily used for Phosphoryla More>>

    merck millipore,默克密理博,539652,PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,539652,PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₁₃F₂N₃O₂145915-60-2
    描述
    概述 A cell-permeable symmetrical phthalimide compound that acts as a potent, reversible, and ATP-competitive inhibitor of EGFR and PKC isozymes α, βI, and βII (IC50 = 0.7 µM, 1.9 µM, 3.8 µM, and 0.41 µM, respectively). Only weakly inhibits the activity of a panel of 16 other kinases, including novel and atypical PKC isozymes. Reported to inhibit insulin-stimulated cellular 2-deoxyglucose uptake, osteoclast differentiation, ERK activation, and TLS/FUS DNA-binding activity in vitro. Also reported to exhibit antitumor activity in mice in vivo.
    产品目录编号 539652
    品牌系列 Calbiochem®
    同义词 CG53353, DAPH 2, 4,5-bis(4-Fluoroanilino)-phthalimide, CGP 53 353
    参考
    参考 Kouroedov, A., et al. 2004. Circulation 110, 91.
    Lee, S.W., et al. 2003. Bone 32, 217.
    Perrotti, D., et al. 1998. EMBO J. 17, 4442.
    Chalfant, C.E., et al. 1996. Mol. Endocrinol. 10, 1273.
    Buchdunger, E., et al. 1995. Clin. Cancer Res. 1, 813.
    Trinks, U., et al. 1994. J. Med. Chem. 37, 1015.
    产品信息
    CAS号 145915-60-2
    具有ATP竞争性 Y
    形式 Orange solid
    Hill配方 C₂₀H₁₃F₂N₃O₂
    化学配方 C₂₀H₁₃F₂N₃O₂
    Molar Mass 365.3
    可逆 Y
    结构配方图像
    生物信息
    主靶 EGFR
    主靶IC50 0.7 µM, 1.9 µM, 3.8 µM, and 0.41 µM against EGFR and PKC isozymes α, βI, and βII, respectively
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,539652,PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,233480,Coagulation Factor XI, Human Plasma
下一件merck millipore产品：merck millipore,默克密理博,ABT162,Anti-GCC185 Antibody


相关产品

merck millipore,默克密理博,AB2969,Anti-Gelsolin Antibody merck millipore,默克密理博,AB2969,Anti-Gelsolin Antibody

merck millipore,默克密理博,04-1525,Anti-TAFII250 Antibody, clone 6B3 merck millipore,默克密理博,04-1525,Anti-TAFII250 Antibody, clone 6B3

merck millipore,默克密理博,CBL479,Anti-Integrin β3 Antibody, clone PM6/13 merck millipore,默克密理博,CBL479,Anti-Integrin β3 Antibody, clone PM6/13

merck millipore,默克密理博,298711,Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem merck millipore,默克密理博,298711,Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem

merck millipore,默克密理博,233480,Coagulation Factor XI, Human Plasma merck millipore,默克密理博,233480,Coagulation Factor XI, Human Plasma

merck millipore,默克密理博,ABT162,Anti-GCC185 Antibody merck millipore,默克密理博,ABT162,Anti-GCC185 Antibody

merck millipore,默克密理博,401515,Rabbit Anti-Goat IgG, H & L Chain Specific Peroxidase Conjugate merck millipore,默克密理博,401515,Rabbit Anti-Goat IgG, H & L Chain Specific Peroxidase Conjugate

merck millipore,默克密理博,SF-855,miR-339-3p; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-855,miR-339-3p; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,07-1514,Anti-phospho-WAVE2 (Ser351) Antibody merck millipore,默克密理博,07-1514,Anti-phospho-WAVE2 (Ser351) Antibody

merck millipore,默克密理博,04-796,Anti-Akt1/PKBα Antibody, clone AW24,04-796 merck millipore,默克密理博,04-796,Anti-Akt1/PKBα Antibody, clone AW24,04-796


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部