merck millipore,默克密理愽
  • merck millipore,默克密理博,524748,PDE4D Inhibitor, GEBR-7b - Calbiochem

  • merck millipore,默克密理博,524748,PDE4D Inhibitor, GEBR-7b - Calbiochem

    产品名称：PDE4D Inhibitor, GEBR-7b - Calbiochem
    产品型号：524748
    The PDE4D Inhibitor, GEBR-7b controls the biological activity of PDE4D. This small molecule/inhibitor is primarily used for Cell Signaling applications.

    merck millipore,默克密理博,524748,PDE4D Inhibitor, GEBR-7b - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,524748,PDE4D Inhibitor, GEBR-7b - Calbiochem

    重要规格表

    经验配方
    C₂₁H₃₀N₂O₅
    描述
    概述 A cell permeable, potent, and selective oxime PDE4D inhibitor (IC50 = 0.67 µM) which displays much reduced activities toward other PDE4 isoforms. It is shown to cause a significant 40% increase in extracellular cAMP in the hippocampus of freely moving rats in vivo at 100 µM, but has no effect on Aβ levels. This compound elicits cognitive enhancement in vivo at the optimum dose of 0.003 mg/kg in both mice and rat models, and unlike rolipram, does not cause emesis-like behavior in rodents.
    产品目录编号 524748
    品牌系列 Calbiochem®
    同义词 GEBR-7b, (E)-3-(cyclopentyloxy)-4-methoxybenzaldehyde, O-2-(2,6-dimethylmorpholino)-2-oxoethyl oxime
    参考
    参考 Bruno, O., et al. 2011. Br. J. Pharmacol. in press.
    Bruno, O., et al. 2009. J. Med. Chem. 52, 6546.
    产品信息
    形式 Pale yellow semi-solid
    Hill配方 C₂₁H₃₀N₂O₅
    化学配方 C₂₁H₃₀N₂O₅
    Molar Mass 390.47
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,524748,PDE4D Inhibitor, GEBR-7b - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,MAB1527,Anti-Peripherin Antibody, clone 8G2
下一件merck millipore产品：merck millipore,默克密理博,05-1149,Anti-ADP-Ribosylation Factor 6 Antibody, clone 6ARF01


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