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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC822 描述 Anti-LIMP II Antibody Alternate Names - CD36
- Lysosome membrane protein 2
- 85 kDa lysosomal membrane sialoglycoprotein
- LGP85
- CD36 antigen-like 2
- Lysosome membrane protein II
- LIMP II
- Scavenger receptor class B member 2
背景信息 Lysosome membrane protein 2, also known as 85 kDa lysosomal membrane sialoglycoprotein (LGP85) or Lysosome membrane protein II (LIMP II) or Scavenger receptor class B member 2, and encoded by the gene name SCARB2 or CD36L2 or LIMPII, is a heavily glycosylated type III transmembrane protein, the majority of which exists in the lumen of the lysosome and a cytoplasmic domain of approximately 20 amino acids. A deficiency of LIMP II in mice causes uretic pelvic junction obstruction, deafness, and peripheral neuropathy associated with impaired vesicular trafficking and distribution of apically expressed proteins. More recently, LIMP II was shown to act as a receptor to bind β-glucocerebrosidase, the enzyme defective in Gaucher disease, a lysosomal storage disorder. LIMP II-deficient mice showed missorted as well as secreted β-glucocerebrosidase, suggesting that LIMP II also functions as the mannose-6-phosphate-independent trafficking receptor. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-LIMP II Antibody is an antibody against LIMP II for use in western blotting, IHC & immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2.5 μg/mL from a representative lot detected LIMP II in human skeletal muscle tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected LIMP II in human skeletal muscle cells.生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the center region of human LIMP II. 表位 center region 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - LIMPII
- SCARB2
- CD36L2
纯化方法 Antigen Affinity purified UniProt编号 - Q14108
产品使用声明 质量保证 Evaluated by Western Blotting in human skeletal muscle tissue lysate with and without blocking peptide.
Western Blotting Analysis: 1 μg/mL of this antibody detected GPAT-1 in human skeletal muscle tissue lysate with and without blocking peptide.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,480150,Ras-Net (Elk-3) Pathway Inhibitor, XRP44X - CAS 729605-21-4 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,MAB1527,Anti-Peripherin Antibody, clone 8G2
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