- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H, M WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB8230 描述 Anti-Syndecan-1 Antibody Alternate Names - syndecan proteoglycan 1
- CD138 antigen
- heparan sulfate proteoglycan fibroblast growth factor<br />receptor
- syndecan 1
背景信息 Syndecan-1, also known as CD138, is a transmembrane (Type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization. Bearing properties of both heparan sulfate and chondroitin sulfate, Syndecan-1 functions as a cell surface proteoglycan membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. 产品信息 格式 Serum 控制 - Mouse liver lysate
演示 Rabbit serum containing 0.05% NaN3. 应用 应用 Anti-Syndecan-1 Antibody is an antibody against Syndecan-1 for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 His-tagged, full-length human recombinant Syndecan-1 protein. 宿主 Rabbit 特异性 Cat. No. AB8230 recognizes mouse Syndecan-1. 品种反应性 HumanMouse Species Reactivity Note Mouse. Predicted to cross react with human, based on 100% sequence homology. Reactivity with other species has not been tested. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001006946.1
Entrez基因汇总 The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq] 基因符号 - OTTHUMP00000115942
- CD138
- SDC
- SYND1
- syndecan
UniProt编号 - P18827
UniProt汇总 FUNCTION:Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
SUBUNIT STRUCTURE: Interacts with CDCP1.
SUBCELLUAR LOCATION: Membrane; Single-pass type I membrane protein.
SEQUENCE SIMILARITIES: Belongs to the syndecan proteoglycan family.
产品使用声明 质量保证 Evaluated on a representative lot by Western blot on mouse liver lysate using 1:1000 dilution of Anti-Syndecan-1. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C for up to 1 year from date of receipt. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,530389,RIPK3 Inhibitor, GSKʹ872 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,495609,InSolution™ Okadaic Acid, Prorocentrum sp. - Calbiochem
相关产品
merck millipore,默克密理博,12-220,Serine Phosphopeptide (RRApSVA)
merck millipore,默克密理博,14-450M,Cdk1/cyclin B Protein, active, 250 µg
merck millipore,默克密理博,MAB80145,Anti-Newcastle Disease Virus Antibody
merck millipore,默克密理博,AB5762,Anti-LHX5 Antibody
merck millipore,默克密理博,530389,RIPK3 Inhibitor, GSKʹ872 - Calbiochem
merck millipore,默克密理博,495609,InSolution™ Okadaic Acid, Prorocentrum sp. - Calbiochem
merck millipore,默克密理博,71724,pIEx/Bac™-1 DNA - Novagen
