merck millipore,默克密理愽
  • merck millipore,默克密理博,530389,RIPK3 Inhibitor, GSKʹ872 - Calbiochem

  • merck millipore,默克密理博,530389,RIPK3 Inhibitor, GSKʹ872 - Calbiochem

    产品名称：RIPK3 Inhibitor, GSKʹ872 - Calbiochem
    产品型号：530389
    A cell-permeable, selective inhibitor of RIP3-selective kinase with >1,000-fold selectivity over a vast majority of more than 300 other kinases.

    merck millipore,默克密理博,530389,RIPK3 Inhibitor, GSKʹ872 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,530389,RIPK3 Inhibitor, GSKʹ872 - Calbiochem

    重要规格表

    经验配方
    C₁₉H₁₇N₃O₂S₂
    描述
    概述 A cell-permeable quinolinyl-benzothiazolamine compound that is reported to act as a RIP3-selective kinase inhibitor with >1,000-fold selectivity over a vast majority of more than 300 other kinases, including RIP1. RIP1 inhibitor Nec-1 (30 µM; Cat. Nos. 480065 & 505224) can be employed in conjunction with GSK'872 (3 µM) in delineating RIP1- vs. RIP3-dependency in Toll-like receptors- (TLRs) mediated necrosis and TNFR1-initiated necroptosis in the presence or absence of caspase inhibitor Z-VAD-FMK (25 µM; Cat. Nos. 627609 & 627610).
    产品目录编号 530389
    品牌系列 Calbiochem®
    同义词 N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine, RIP3 Kinase Inhibitor I, Receptor-Interacting Protein Kinase 3 Inhibitor I, GSK-872, Necrosis Inhibitor V, RIPK3 Inhibitor I
    参考
    参考 Kaiser, W.J., et al. 2013. J. Biol. Chem. 288, 31268.
    产品信息
    形式 Yellow solid
    Hill配方 C₁₉H₁₇N₃O₂S₂
    化学配方 C₁₉H₁₇N₃O₂S₂
    可逆 Y
    生物信息
    主靶 RIP3 Kinase
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze 9-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,530389,RIPK3 Inhibitor, GSKʹ872 - Calbiochem

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