merck millipore,默克密理愽
  • merck millipore,默克密理博,523310,Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem

  • merck millipore,默克密理博,523310,Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem

    产品名称：Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem
    产品型号：523310
    A cell-permeable methoxylated analog of Resveratrol that displays antioxidant, antiproliferative, and hypoglycemic properties.

    merck millipore,默克密理博,523310,Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,523310,Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₆O₃537-42-8
    描述
    概述 A cell-permeable methoxylated analog of Resveratrol (Cat. No. 554325) that displays antioxidant, antiproliferative, and hypoglycemic properties. Moderately inhibits COX-1 and -2 activities (IC50 = 19.8 µM and 83.9 µM) respectively, induces apoptosis in HL60 cells (IC50 = 70 µM), prevents DMBA-induced preneoplastic lesions (ED50 = 4.8 µM) and decreases plasma glucose level in streptozotocin-induced diabetic rats comparable to that of Metformin.
    产品目录编号 523310
    品牌系列 Calbiochem®
    同义词 trans-3,5-Dimethoxy-4ʹ-hydroxystilbene
    参考
    参考 Roberti, M., et al. 2003. J. Med. Chem. 46, 3546.
    Rimando, A.M., et al. 2002. J. Agric. Food Chem. 50, 3453.
    Manickam, M., et al. 1997. J. Nat. Prod. 60, 609.
    产品信息
    CAS号 537-42-8
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₁₆H₁₆O₃
    化学配方 C₁₆H₁₆O₃
    Molar Mass 256.3
    可逆 N
    结构配方图像
    生物信息
    主靶 COX-1 and COX-2 activities
    主靶IC50 19.8 µM, 83.9 µM against COX-1 and -2 activities, respectively; 70 µM for inducing apoptosis in HL60 cells; ED50 = 4.8 µM for preventing DMBA-induced preneoplastic lesions
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or MeOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,523310,Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem

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