merck millipore,默克密理博,516560,Pertussis Toxin, Bordetella pertussis - CAS 70323-44-3

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merck millipore,默克密理博,516560,Pertussis Toxin, Bordetella pertussis - CAS 70323-44-3 - Calbiochem
产品名称：Pertussis Toxin, Bordetella pertussis - CAS 70323-44-3 - Calbiochem
产品型号：516560
Obtain a uniform suspension before use.

merck millipore,默克密理博,516560,Pertussis Toxin, Bordetella pertussis - CAS 70323-44-3 - Calbiochem

产品介绍

merck millipore,默克密理博,516560,Pertussis Toxin, Bordetella pertussis - CAS 70323-44-3 - Calbiochem

重要规格表

CAS号
70323-44-3

描述
概述	Obtain a uniform suspension before use. A protein endotoxin that catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins G_i, G_o, and G_t. Used in the study of adenylate cyclase regulation and the role of G_i proteins. Holotoxin activity is determined in a CHO cell assay.
概述	NOTE: This product is not activated, hence for use in cell-free systems, activation is required.
产品目录编号	516560
品牌系列	Calbiochem®
同义词	Islet-activating Protein

参考
参考	Joshi, S.A., et al. 1998. FEBS Lett. 441, 67. Fryer, M.W. 1992. Neurosci. Lett. 146, 84. Gierschik, P. 1992. Curr. Topics Microbiol. Immunol. 175, 69. Harada, J., et al. 1992. Eur. J. Pharmacol. 227, 301. Hausman, S.Z., and Burns, D.L. 1992. J. Biol. Chem. 267, 13735. Kaslow, H.R., and Burns, D.L., 1992. FASEB J. 6, 2684. Zhu, J., et al. 1992. J. Pharmacol. Exp. Therap. 263, 1479. Hewlett, E.L., et al. 1983. Infect. Immun. 40, 1198. Moss, J., et al. 1983. J. Biol. Chem. 258, 11879.

参考

Joshi, S.A., et al. 1998. FEBS Lett. 441, 67.
Fryer, M.W. 1992. Neurosci. Lett. 146, 84.
Gierschik, P. 1992. Curr. Topics Microbiol. Immunol. 175, 69.
Harada, J., et al. 1992. Eur. J. Pharmacol. 227, 301.
Hausman, S.Z., and Burns, D.L. 1992. J. Biol. Chem. 267, 13735.
Kaslow, H.R., and Burns, D.L., 1992. FASEB J. 6, 2684.
Zhu, J., et al. 1992. J. Pharmacol. Exp. Therap. 263, 1479.
Hewlett, E.L., et al. 1983. Infect. Immun. 40, 1198.
Moss, J., et al. 1983. J. Biol. Chem. 258, 11879.

产品信息
CAS号	70323-44-3
具有ATP竞争性	N
形式	Lyophilized
配方	Lyophilized from 50 mM NaCl, 10 mM sodium phosphate buffer, pH 7.0.
可逆	N

生物信息
主靶	Guanine nucleotide-binding regulatory proteins Gi, Go, and Gt
纯度	Five distinct bands by SDS-PAGE

理化信息
细胞可渗透	N
污染物	Adenylate cyclase activity: ≤35 pmol/min/µg in the presence of calmodulin
溶解度	Sterile dH₂O

GHS安全信息
RTECS	XW5883750

安全信息
R相	R: 23/24/25 Toxic by inhalation, in contact with skin and if swallowed.
S相	S: 36/37/39-45 Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Toxic
有害材料注意事项：	Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存	+2°C to +8°C
无需冷冻	Yes
特殊指南	Following reconstitution, refrigerate (4°C). For long-term storage in solution, reconstitute with a high ionic strength buffer, such as 100 mM sodium phosphate, 500 mM sodium chloride, pH 7.0. Stock solutions are stable for at least 6 months for use in CHO cell assays and for 1-2 months for use in non-cellular systems.
加拿大出口规定	Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.