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merck millipore,默克密理博,506163,p38 MAP Kinase Inhibitor VIII - CAS 321351-00-2 - Calbiochem
产品名称：p38 MAP Kinase Inhibitor VIII - CAS 321351-00-2 - Calbiochem
产品型号：506163
The p38 MAP Kinase Inhibitor VIII, also referenced under CAS 321351-00-2, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Deph More>>
merck millipore,默克密理博,506163,p38 MAP Kinase Inhibitor VIII - CAS 321351-00-2 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₀H₁₆BrClN₂O 321351-00-2 描述 概述 A cell-permeable aminobenzophenone compound that acts as a potent, ATP-binding pocket-targeting inhibitor against p38α and p38β2 (82% and 93% inhibition with 1 µM inhibitor, respectively; IC50 of p38α inhibition = 40 nM) with little activity against a panel of 57 other kinases, including p38γ, p38δ, Erk1/2, and JNK1. Shown to inhibit LPS-induced cytokine productions in human PBMC's in vitro and exhibit in vivo efficacy in both acute and chronic murine models of skin inflammation. 产品目录编号 506163 品牌系列 Calbiochem®
同义词 (4-((2-Amino-4-bromophenyl)amino)-2-chlorophenyl)-(2-methylphenyl)methanone 参考 参考 Ottosen, E.R., et al. 2003. J. Med. Chem. 46, 5651. 产品信息 CAS号 321351-00-2 形式 Yellow solid Hill配方 C₂₀H₁₆BrClN₂O 化学配方 C₂₀H₁₆BrClN₂O Molar Mass 415.7 结构配方图像 生物信息 纯度 ≥97% by HPLC 理化信息 溶解度 DMSO or EtOH 安全信息 S相 S: 22-24/25-36/37/39-45
Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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