merck millipore,默克密理愽
  • merck millipore,默克密理博,496150,Omi/HtrA2 Protease Inhibitor, Ucf-101 - CAS 313649-08-0 - Calbiochem

  • merck millipore,默克密理博,496150,Omi/HtrA2 Protease Inhibitor, Ucf-101 - CAS 313649-08-0 - Calbiochem

    产品名称：Omi/HtrA2 Protease Inhibitor, Ucf-101 - CAS 313649-08-0 - Calbiochem
    产品型号：496150
    The Omi/HtrA2 Protease Inhibitor, Ucf-101, also referenced under CAS 313649-08-0, controls the biological activity of Omi/HtrA2 Protease. This small molecule/inhibitor is primarily used for Cancer app More>>

    merck millipore,默克密理博,496150,Omi/HtrA2 Protease Inhibitor, Ucf-101 - CAS 313649-08-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,496150,Omi/HtrA2 Protease Inhibitor, Ucf-101 - CAS 313649-08-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₇H₁₇N₃O₅S313649-08-0
    描述
    概述 A cell-permeable furfurylidine-thiobarbituric acid compound that acts as a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, heat-inducible, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 µM for His-Omi134-458). Shows very little activity against various other serine proteases tested (IC50 ≥ 200 µM). Reported to block Omi/HtrA2 induced cell death in caspase-9 (-/-) null fibroblasts.
    产品目录编号 496150
    品牌系列 Calbiochem®
    同义词 High Temperature Requirement A2 Inhibitor I, 5-[5-(2-Nitrophenyl)furfurylidine]-1,3-diphenyl-2-thiobarbituric Acid
    参考
    参考 Cilenti, L., et al. 2003. J. Biol. Chem. 278, 11489.
    产品信息
    CAS号 313649-08-0
    具有ATP竞争性 N
    形式 Orange solid
    Hill配方 C₂₇H₁₇N₃O₅S
    化学配方 C₂₇H₁₇N₃O₅S
    Molar Mass 495.5
    可逆 Y
    结构配方图像
    生物信息
    主靶 pro-apoptotic, heat-inducible, mitochondrial serine protease Omi/HtrA2
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,496150,Omi/HtrA2 Protease Inhibitor, Ucf-101 - CAS 313649-08-0 - Calbiochem

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