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经验配方 CAS号 C₁₅H₁₀O₄ 486-66-8 描述 概述 Inactive analog of Genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss/3T3 cells by inhibiting casein kinase II activity. Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively). 产品目录编号 251600 品牌系列 Calbiochem®
同义词 4ʹ,7-Dihydroxyisoflavone, Casein Kinase II Inhibitor X 参考 参考 Guo, J-M., et al. 2004. World J. Gastroenterol. 10, 860.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol. 7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem. 262, 5592.
产品信息 CAS号 486-66-8 具有ATP竞争性 N 形式 Off-white solid Hill配方 C₁₅H₁₀O₄ 化学配方 C₁₅H₁₀O₄ Molar Mass 254.2 可逆 N 结构配方图像 生物信息 主靶 MiaPaC-2, PANC-1 主靶IC50 45 µM, 75 µM for inhibiting the growth of MiaPaC-2 and PANC-1 cells, respectively 纯度 ≥98% by TLC 理化信息 细胞可渗透 N 溶解度 DMSO GHS安全信息 RTECS DJ3100040 安全信息 R相 R: 36/38
Irritating to eyes and skin.S相 S: 24-26
Avoid contact with skin.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C) under an inert gas. DMSO stock solutions are stable for up to 2 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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