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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN509 描述 Anti-SV2C Antibody Alternate Names - SV2C
- Synaptic vesicle glycoprotein 2C
背景信息 The protein named Synaptic vesicle glycoprotein 2C (SV2C) and encoded by the human name named SV2C/KAA1054 is glycosylated membrane bound protein important in vesicle secretion. SV2C is part of the major facilitator superfamily of vesicle movement and fusion proteins and is particularly important is vesicle fusion by maintaining a readily releasable pool of secretory granules. Expressed in neural and endocrine cells primarily, SV2C is important for neurotransmission and hormone release. SV2C is enriched in small synaptic vesicles and adrenal microsomes but it is not present in chromaffin granules but is found in insulin granules and microvesicles in the pancreas. In the brain SV2C, in contrast to SV2A and SV2B, expression is restricted to certain regions. High levels of SV2C are found primarily in phylogenetically old brain regions such as the pallidum, the substantia nigra, the midbrain, the brainstem and the olfactory bulb, but SV2C is undetectable in the cerebral cortex and the hippocampus, and found at low levels in the cerebellar cortex. Recent research though also demonstrates that SV2C plays an important role in normal operation of the basal ganglia network and SV2C could also be involved in system adaptation during basal ganglia pathology. We offer a rabbit polyclonal Anti-SV2C Antibody that has been validated in western blot on mouse brain lysate. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Detect SV2C using this rabbit polyclonal antibody, Anti-SV2C Antibody validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged fusion protein corresponding to human SV2C. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Mouse 抗体类型 Polyclonal Antibody 基因符号 - KIAA1054
- SV2C
纯化方法 Antigen Affinity purified UniProt编号 - Q496J9
产品使用声明 质量保证 Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected SV2C in mouse brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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