merck millipore,默克密理愽
  • merck millipore,默克密理博,203694,bpV(bipy) - Calbiochem

  • merck millipore,默克密理博,203694,bpV(bipy) - Calbiochem

    产品名称：bpV(bipy) - Calbiochem
    产品型号：203694
    A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation).

    merck millipore,默克密理博,203694,bpV(bipy) - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,203694,bpV(bipy) - Calbiochem

    重要规格表

    经验配方
    K[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
    描述
    概述 A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation). An activator of insulin receptor kinase (IRK). Also reported to be a potent inhibitor of PTEN (IC50 = 18 nM).
    产品目录编号 203694
    品牌系列 Calbiochem®
    同义词 Potassium Bisperoxo(bipyridine)oxovanadate (V), PTEN Inhibitor II, PTP Inhibitors XIV
    参考
    参考 Schmid, A.C., et al. 2004. FEBS Lett. 566, 35.
    Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.
    产品信息
    具有ATP竞争性 N
    形式 Yellow to orange solid
    Hill配方 K[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
    化学配方 K[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
    Molar Mass 380.3
    可逆 N
    结构配方图像
    生物信息
    主靶 phosphotyrosine phosphatase
    主靶IC50 18 nM against PTEN
    主靶Ki 100 nM for phosphotyrosine phosphatase
    纯度 ≥95% by ⁵¹V-NMR
    理化信息
    细胞可渗透 N
    溶解度 H₂O
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Unstable in solution; reconstitute just prior to use.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,203694,bpV(bipy) - Calbiochem

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