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经验配方 CAS号 C₂₀H₃₉NO₂ 111-58-0 描述 概述 A potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM). 产品目录编号 495417 品牌系列 Calbiochem®
同义词 N-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA 参考 参考 Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
Sugita, M., et al. 1975. Biochim. Biophys. Acta 398, 125.产品信息 CAS号 111-58-0 具有ATP竞争性 N 形式 White solid Hill配方 C₂₀H₃₉NO₂ 化学配方 C₂₀H₃₉NO₂ Molar Mass 325.5 可逆 N 结构配方图像 生物信息 主靶 Acid ceramidase 主靶IC50 ~ 500 µM against acid ceramidase 纯度 ≥98% by TLC 理化信息 细胞可渗透 N 溶解度 EtOH, Chloroform, or MeOH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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