merck millipore,默克密理博,371208,Dkk-1, Rat, Recombinant

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,371208,Dkk-1, Rat, Recombinant
产品名称：Dkk-1, Rat, Recombinant
产品型号：371208

merck millipore,默克密理博,371208,Dkk-1, Rat, Recombinant

产品介绍

merck millipore,默克密理博,371208,Dkk-1, Rat, Recombinant

重要规格表

纯度
≥95% by SDS-PAGE

描述
概述	Recombinant, rat Dickkopf related protein-1 (Dkk-1), consisting of amino acids 23-270, fused at the C-terminus to a His•Tag^® sequence, and expressed in NS0-derived mouse myeloma cells. The balance between Wnt signaling and Dkk-1 inhibition is essential for bone formation and homeostasis.
产品目录编号	371208
品牌系列	Calbiochem®

参考
参考	Li, J. et al. 2006. Bone 36, 754. Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934. Niehrs, C. 2006. Oncogene 25, 7469. Verani, R. et al. 2006. J. Neurochem. 101, 242. Cappuccio, I. et al. 2005. J. Neurosci. 25, 2647. Kemp, C. et al. 2005. Dev. Dyn. 233, 1064. Adamska, M. et al. 2004. Dev. Biol. 272, 134. Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582. Mao, B. et al. 2002. Nature 417, 664. Mao, B. et al. 2001. Nature 411, 321. Krupnik, V.E., et al. 1999. Gene 238, 301.

参考

Li, J. et al. 2006. Bone 36, 754.
Morvan, F. et al. 2006. J. Bone Miner. Res. 21, 934.
Niehrs, C. 2006. Oncogene 25, 7469.
Verani, R. et al. 2006. J. Neurochem. 101, 242.
Cappuccio, I. et al. 2005. J. Neurosci. 25, 2647.
Kemp, C. et al. 2005. Dev. Dyn. 233, 1064.
Adamska, M. et al. 2004. Dev. Biol. 272, 134.
Bullock, C.M. et al. 2004. Mol. Pharmacol. 65, 582.
Mao, B. et al. 2002. Nature 417, 664.
Mao, B. et al. 2001. Nature 411, 321.
Krupnik, V.E., et al. 1999. Gene 238, 301.

产品信息
形式	Lyophilized
配方	Lyophilized from 0.2 µm filtered PBS, BSA.
Molar Mass	27600

生物信息
生物活性	ND₅₀ = 0.1-0.5 µg/ml as measured by inhibition of Wnt-3a-induced (10 ng/ml rmWnt-3a) alkaline phosphatase production by proliferation of MC3T3-E1 mouse osteoblastic cells.
纯度	≥95% by SDS-PAGE

理化信息
污染物	Endotoxin: ≤1.0 EU/µg protein
溶解度	PBS

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.