merck millipore,默克密理愽
  • merck millipore,默克密理博,492000,NOX Inhibitor III, VAS2870 - CAS 722456-31-7 - Calbiochem

  • merck millipore,默克密理博,492000,NOX Inhibitor III, VAS2870 - CAS 722456-31-7 - Calbiochem

    产品名称：NOX Inhibitor III, VAS2870 - CAS 722456-31-7 - Calbiochem
    产品型号：492000
    The NOX Inhibitor III, VAS2870, also referenced under CAS 722456-31-7, controls the biological activity of NOX.

    merck millipore,默克密理博,492000,NOX Inhibitor III, VAS2870 - CAS 722456-31-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,492000,NOX Inhibitor III, VAS2870 - CAS 722456-31-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₁₂N₆OS722456-31-7
    描述
    概述 A cell-permeable thiotriazolopyrimidine compound that acts as an effective NADPH oxidase (NOX) inhibitor (IC50 = 10.6 µM against NOX activity in human neutrophil lysates) and is widely used for studying NOX-dependent cellular ROS formations in various cultures, including oxLDL-treated HUVEC (complete inhibition at 5 µM), PDGF-induced primary rat VSMC (vascular smooth muscle cells; complete inhibition at 10 µM), as well as aortic sections from spontaneously hypertensive rats (72% inhibition at 10 µM) ex vivo.
    产品目录编号 492000
    品牌系列 Calbiochem®
    同义词 7-(1,3-Benzoxazol-2-ylsulfanyl)-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine, 1,3-Benzoxazol-2-yl-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide, NADPH Oxidase Inhibitor III, VAS2870
    参考
    参考 Wind, S., et al. 2010. Hypertension 56, 490.
    Lange, S., et al. 2009. Cardiovasc. Res. 81, 159.
    Stielow, C., et al. 2006. Biochem. Biophys. Res. Commun. 344, 200.
    ten Freyhaus, H., et al. 2006. Cardiovasc. Res. 71, 331.
    产品信息
    CAS号 722456-31-7
    形式 Tan solid
    Hill配方 C₁₈H₁₂N₆OS
    化学配方 C₁₈H₁₂N₆OS
    Molar Mass 360.4
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,492000,NOX Inhibitor III, VAS2870 - CAS 722456-31-7 - Calbiochem

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