• merck millipore,默克密理博,487929,InSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem
  • merck millipore,默克密理博,487929,InSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem

    产品名称:InSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem
    产品型号:487929
    Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture.

    merck millipore,默克密理博,487929,InSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,487929,InSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₄H₁₁N₃O₃S31430-18-9
    描述
    概述 Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture. Promotes tubulin depolymerization. Also acts as a high-affinity ligand for the cancer-related kinases ABL, c-KIT, BRAF, and MEK (Kd < 2 µM). The solid form of this compound (Cat. No. 487928) is also available.
    产品目录编号 487929
    品牌系列 Calbiochem®
    同义词 R17934, Methyl-(5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamate, Methyl-5-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-ylcarbamate
    参考
    参考 Park, H., et al. 2012. Chem. Med. Chem. 7, 53.
    Bunz, F., et al. 1998. Science 282, 1497.
    Fleischman, L.F., et al. 1993. Oncogene 8, 771. Pomies, P., and Block, M.R. 1992. Biochem. Biophys. Res. Commun. 189, 1429.
    Rennison, M.E., et al. 1992. J. Cell Sci. 102, 239.
    Thyberg, J., and Moskalewski, S. 1992. J. Cell Sci. 103, 1167.
    产品信息
    CAS号 31430-18-9
    形式 Liquid
    配方 A 50 mM (10 mg/664 µL) solution of Nocodazole (Cat. No. 487928) in DMSO.
    Hill配方 C₁₄H₁₁N₃O₃S
    Molar Mass 301.3
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 Microtubules
    副靶 Certain kinases
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    安全信息
    R相 R: 36/38

    Irritating to eyes and skin.
    S相 S: 26-36-45

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Irritant
    储存 ≤ -70°C
    避光 Protect from light
    吸湿 Hygroscopic
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 1 year at -70°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,487929,InSolution™ Nocodazole - CAS 31430-18-9 - Calbiochem

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