• merck millipore,默克密理博,480748,Neuronal Differentiation Inducer, Isobavachin - Calbiochem
  • merck millipore,默克密理博,480748,Neuronal Differentiation Inducer, Isobavachin - Calbiochem

    产品名称:Neuronal Differentiation Inducer, Isobavachin - Calbiochem
    产品型号:480748
    A cell-permeable, 8-prenyl flavone that is shown to induce differentiation of mouse embryonic stem (ES) cells into neuronal cells and astrocytes, at 100 nM.

    merck millipore,默克密理博,480748,Neuronal Differentiation Inducer, Isobavachin - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,480748,Neuronal Differentiation Inducer, Isobavachin - Calbiochem

    重要规格表

    经验配方
    C₂₀H₂₀O₄
    描述
    概述 A cell-permeable, 8-prenyl flavone that is shown to induce differentiation of mouse embryonic stem (ES) cells into neuronal cells and astrocytes, at 100 nM. It is shown to elicit the down-regulation of p38 and JNK phosphorylation, and the up-regulation of ERK phosphorylation. Co-treatment with GGTI-298 (1000 nM), a Geranylgeranyltransferase I Inhibitor (Cat. No. 345883) selectively abolishes the IBA- but not Retinoic Acid-induced neuronal differentiation, which suggests that the differentiation inducing effect may involve protein prenylation.
    产品目录编号 480748
    品牌系列 Calbiochem®
    同义词 Isobavachin, 7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chroman-4-one
    参考
    参考 Wang, D.Y., et al. 2011. Acta Pharmacol Sin 32, 425.
    产品信息
    形式 Pale yellow solid
    Hill配方 C₂₀H₂₀O₄
    化学配方 C₂₀H₂₀O₄
    Molar Mass 324.37
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,480748,Neuronal Differentiation Inducer, Isobavachin - Calbiochem

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