merck millipore,默克密理愽
  • merck millipore,默克密理博,480060,Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem

  • merck millipore,默克密理博,480060,Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem

    产品名称：Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem
    产品型号：480060
    The Necrosis Inhibitor, IM-54, also referenced under CAS 861891-50-1, selectively blocks oxidative stress-induced necrotic cell death. This small molecule/inhibitor is primarily used for Cancer applic More>>

    merck millipore,默克密理博,480060,Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,480060,Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₂₃N₃O₂861891-50-1
    描述
    概述 A cell-permeable mono-indolylmaleimide compound that selectively blocks oxidative stress-induced necrotic cell death (~3 µM IM-54 prevented ~50% cell death in HL60 cells exposed to 100 µM H2O2). Does not offer protection against Etoposide- (Cat. No. 341205) induced apoptosis or display antioxidant properties. Does not affect the kinase activities of S6K1 and PKC isozymes even at concentrations as high as 50 µM.
    产品目录编号 480060
    品牌系列 Calbiochem®
    同义词 2-(1H-Indol-3-yl)-3-pentylamino-maleimide
    参考
    参考 Dodo, K., et al. 2005. Bioorg. Med. Chem. Lett. 15, 3114.
    产品信息
    CAS号 861891-50-1
    具有ATP竞争性 N
    形式 Yellow orange solid
    Hill配方 C₁₉H₂₃N₃O₂
    化学配方 C₁₉H₂₃N₃O₂
    Molar Mass 325.4
    可逆 N
    结构配方图像
    生物信息
    主靶 Blocks oxidative stress-induced necrotic cell death
    主靶IC50 (~3 µM prevented ~50% cell death in HL60 cells exposed to 100 µM H₂O₂).
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or MeOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,480060,Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,09-818,Anti-CARM1 Antibody


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