merck millipore,默克密理博,48-630MAG,MILLIPLEXMAP NF-κB Signaling Magnetic Bead Kit 6-plex Kit

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merck millipore,默克密理博,48-630MAG,MILLIPLEXMAP NF-κB Signaling Magnetic Bead Kit 6-plex Kit - Cell Signaling Multiplex Assay

可用的分析物	品种反应性	主要应用	检测方法
TNFR1, c-Myc, FADD (Ser194), IκBα (Ser32), IKKα/β (Ser177/Ser181), NFκB (Ser536)	H	Mplex	Luminex xMAP

描述
产品目录编号	48-630MAG
商名	MILLIPLEX
描述	MILLIPLEXMAP NF-κB Signaling Magnetic Bead Kit 6-plex Kit - Cell Signaling Multiplex Assay
概述	NF-κB (nuclear factor kappa B) is a transcription factor that plays a regulatory role in several physiological and pathological processes. The NF-κB pathway can be activated by numerous stimuli, including inflammatory cytokines, virus, bacteria, UV radiation, genotoxic stress, DNA damage, oxidative stress, etc. The IkBα/NF-κB complex is tightly regulated by both phosphorylation and ubiquitination. Phosphorylation and ubiquitination of IκBα leads to its degradation and subsequent release of phosphorylated NF-κB to the nucleus. Greater than 100 target genes, including cytokines, cyclins, p21, Bcl-2, and c-Myc are known to be transcribed by NF-kB.

应用
应用	This MILLIPLEX MAP NF-κB Signaling Magnetic Bead Kit 6-plex Kit is a Cell Signaling multiplex assay. The analytes available for this multiplex kit are: c-Myc (total), FADD (Ser194), IKKα/β (Ser177/Ser181), IκBα (Ser32), NF-κB (Ser536), TNFR1 (total).
主要应用	Multiplexing
应用说明	o This is an overnight (4°C) incubation assay. o This kit must be run using the provided Assay Buffer. o This assay requires 25 μL diluted filtered cell lysate per well. o The suggested working range of protein concentration for the assay is 1 to 25 µg of total protein/well (25 µL/well at 40 to 1,000 µg/mL).

生物信息
特异性	Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
品种反应性	Human
可用的分析物	TNFR1 c-Myc FADD (Ser194) IκBα (Ser32) IKKα/β (Ser177/Ser181) NFκB (Ser536)
化验面板	Premixed beads for your convenience.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Recommended storage for kit components is 2 - 8°C.

包装信息
数量	96-well plate
包装	96-well plate

merck millipore,默克密理博,48-630MAG,MILLIPLEXMAP NF-κB Signaling Magnetic Bead Kit 6-plex Kit - Cell Signaling Multiplex Assay

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