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merck millipore,默克密理博,475867,Mn-cpx 3 - Calbiochem
产品名称：Mn-cpx 3 - Calbiochem
产品型号：475867
A cell-permeable manganese complex of 7-hydroxyflavone that acts as a superoxide dismustase (SOD) mimetic and a neuroprotective agent against radical-induced damages.
merck millipore,默克密理博,475867,Mn-cpx 3 - Calbiochem
- 产品介绍
重要规格表
经验配方 C₃₀H₂₀Cl₂MnO₆ 描述 概述 A cell-permeable manganese complex of 7-hydroxyflavone that acts as a superoxide dismustase (SOD) mimetic and a neuroprotective agent against radical-induced damages. Shown to prevent the reduction of NBT by O2– • (IC50 = 1.18 µM) and exhibit ~10 times higher potency than Trolox (Cat. No. 648471) in inhibiting lipid peroxidation (IC50 = 6.15 µM) in vitro. Suppresses MAP (methamphetamine)-induced brain hypermotility in mice and shows protective effects against learning and memory impairment in a murine ischemic model in vivo. 产品目录编号 475867 品牌系列 Calbiochem®
参考 参考 Vajragupta, O., et al. 2003. Bioorg. Med. Chem. 11, 2329. 产品信息 具有ATP竞争性 N 形式 Pale yellow solid Hill配方 C₃₀H₂₀Cl₂MnO₆ 化学配方 C₃₀H₂₀Cl₂MnO₆ Molar Mass 602.3 可逆 N 结构配方图像 生物信息 主靶 Superoxide dismustase (SOD) mimetic 主靶IC50 1.18 µM in preventing the reduction of NBT by O2- • in vitro 纯度 ≥98% by elemental analysis 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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