merck millipore,默克密理愽
  • merck millipore,默克密理博,475864,MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem

  • merck millipore,默克密理博,475864,MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem

    产品名称：MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem
    产品型号：475864
    The MK-2 Inhibitor III, also referenced under CAS 1186648-22-5, controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applic More>>

    merck millipore,默克密理博,475864,MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,475864,MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₁H₁₆N₄O • H₂O1186648-22-5
    描述
    概述 A cell-permeable pyrrolopyridinyl compound that acts as an ATP-competitive inhibitor of MK-2/MAPKAP-K2 (IC50 = 8.5, 81, and 210 nM against MK-2, MK-5, and MK-3, respectively), while exhibiting much less or no activity against 8 other commonly studied kinases. Shown to suppress LPS-induced TNF-α production in U937 cells (IC50 = 4.4 µM).
    产品目录编号 475864
    品牌系列 Calbiochem®
    同义词 2-(2-Quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo-[3,2-c]pyridin-4-one
    参考
    参考 Anderson, D.R., et al. 2007. J. Med. Chem. 50, 2647.
    产品信息
    CAS号 1186648-22-5
    形式 Pale yellow solid
    Hill配方 C₂₁H₁₆N₄O • H₂O
    化学配方 C₂₁H₁₆N₄O • H₂O
    Molar Mass 358.4
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,475864,MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,528112,PI 3-Kγ/CKII Inhibitor - CAS 1138220-19-5 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,17-285,TCF Reporter Plasmid Kit


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