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经验配方 CAS号 C₁₂H₉N₃O 78415-72-2 描述 概述 A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC50 = 300 nM). Has positive chronotropic, inotropic, and vasodilatory effects on the heart. 产品目录编号 475840 品牌系列 Calbiochem®
同义词 1,6-Dihydro-2-methyl-6-oxo-(3,4ʹ-bipyridine)-5-carbonitrile 参考 参考 Bailey, J.M., et al. 1994. Anesthesiology 81, 616.
Wilhelm, D., et al. 1992. J. Cardiovasc. Pharmacol. 20, 705.
Lindgren, S.H., et al. 1990. Acta. Phys. Scand. 140, 209.
Harrison, S.A., et al. 1986. Mol. Pharmacol. 29, 506.产品信息 CAS号 78415-72-2 具有ATP竞争性 N 形式 White solid Hill配方 C₁₂H₉N₃O 化学配方 C₁₂H₉N₃O 可逆 N 结构配方图像 生物信息 主靶 PDE 3 主靶IC50 300 nM against PDE III 纯度 ≥99% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or EtOH GHS安全信息 RTECS DW1762000 安全信息 R相 R: 23/24/25
Toxic by inhalation, in contact with skin and if swallowed.S相 S: 36/37/39-45
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Toxic
有害材料注意事项: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
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